The school-running tenet of “Seek True Learning， Serve Practical Industry” represents a vital intellectual achievement of the localized exploration of modern Chinese higher education. Centered on the core value of “pragmatism”， this tenet forms a dialectically integrated organic whole. “Seeking true learning” means pursuing genuine knowledge， exploring truth， and adhering to original aspirations， embodying the rigorous scholarly philosophy of investigating things to attain knowledge. “Serving practical industry” emphasizes diligent practice， proficient application， and commitment to social missions， reflecting the pragmatic character of integrating knowledge with action. In the new era， the four Jiaotong Universities should uphold this century-old school-running tenet by continuing their time-honored educational traditions and consolidating the cultural foundation for national development. It is essential to focus on national strategic needs， build a highland for independent talent cultivation， innovate collaborative education models， promote in-depth integration of learning， research， industry and education， and improve long-term guarantee mechanisms to ensure the effective implementation of the school-running tenet.