China-Europe Railway Express is a major innovation in the field of international railway intermodal transport， as well as a model of implementation of the “Belt and Road” initiative and a necessary link for deepening international cooperation. It has gone through several stages， including early exploration and nurturing， regular and large-scale development， integrative construction and standardization， layout transformation， and consolidation and enhancement of the quality of the development. The construction and development of China-Europe Railway Express has brought about a new situation of international transport， explored a new path of railway reform， and opened a new chapter of opening up for inland area， which is of great significance and value for enhancing the resilience of international trade and transport system， deepening the supply-side structural reform of China’s railway industry， and helping the inland areas of the Asian-European continent to better integrate into the open global economy. It provides successful experience in combining top-level design with local exploration， carrying out multi-tiered and multi-dimensional cooperation， and adhering to the mode of innovation-driven and bottom-line thinking， etc. In the future， we should implement the new development philosophy and focus on high-quality development， balance the functions of the government and the market forces and adhere to market-oriented development， strengthen coordination and linkage to enhance the coordinated development in the region， and coordinate development and safety and adhere to the diversified development. With these steps， China-Europe Railway Express will move towards higher quality， greater benefits and more safety.